Easy Low Carb Pizza Casserole – Cheesy & Family-Approved

Craving pizza but watching your carbs? This easy low carb pizza casserole is the perfect solution! After making it countless times, I’ve discovered the trick to a crispy, golden crust. Keep reading for my best tips, or jump straight to the recipe. If you love recipes like this, you’ll also enjoy Moist Double Chocolate Zucchini Bread Recipe Easy Fudgy Goodness and Fresh Grilled Chicken Caesar Salad Recipe with Easy Crispy Garlic Croutons.

Why This Easy Low Carb Pizza Casserole – Cheesy & Family-Approved Is Pure Comfort
- Crispy, golden crust
- Melty, gooey cheese
- Flavorful, homemade pizza sauce
- Easy to customize with your favorite toppings
What You'll Need for Easy Low Carb Pizza Casserole – Cheesy & Family-Approved
Choosing the right ingredients makes a big difference, but this recipe is forgiving enough to work with what you have.
- 1 lb ground beef
- 1 cup shredded mozzarella cheese
- 1 cup shredded cheddar cheese
- 1 cup pizza sauce
- 1 cup shredded pepperoni
- 1 tsp Italian seasoning
- 1 tsp garlic powder
- 1 tsp onion powder
- Salt and pepper to taste
- Optional: Sliced bell peppers
- Optional: Sliced onions
- Optional: Mushrooms
- Optional: Olives
- Optional: Artichoke hearts

📝 Ingredient Notes
- ground beef: You can also use ground turkey or Italian sausage.
🛒 Tools & Equipment I Recommend
- Non-stick skillet — Ensures even cooking and easy cleanup. → See on Amazon
- Casserole dish — Perfect for baking and serving this casserole. → See on Amazon

How to Make Easy Low Carb Pizza Casserole – Cheesy & Family-Approved
- Step 1: Preheat your oven to 375°F (190°C). In a large non-stick skillet, cook the ground beef over medium heat until browned. Drain excess fat.
- Step 2: Stir in the Italian seasoning, garlic powder, onion powder, salt, and pepper. Cook for an additional 2 minutes.
- Step 3: Spread the cooked meat evenly in the bottom of a greased 9×13-inch casserole dish.
- Step 4: Spread the pizza sauce over the meat, then sprinkle with half of the mozzarella and cheddar cheeses.
- Step 5: Add your desired toppings, then sprinkle with the remaining cheese.
- Step 6: Bake for 20-25 minutes, or until the cheese is bubbly and golden. Let it rest for 5 minutes before serving.
Cook's Tips for Perfect Easy Low Carb Pizza Casserole – Cheesy & Family-Approved
- Common mistake and fix: Don't overcook the casserole. Keep an eye on it to prevent the cheese from burning.
- Pro tip: For a crispier crust, bake the casserole on a preheated baking sheet.
- Pro tip: To make this casserole ahead, prepare it up to the baking step, then refrigerate. Bake as directed when ready to serve.
Storing & Reheating Easy Low Carb Pizza Casserole – Cheesy & Family-Approved
Short-Term Storage
Store in an airtight container in the fridge. Store leftovers in an airtight container in the fridge for up to 4 days. Make-ahead tip: You can assemble this casserole up to 24 hours ahead. Store in the fridge, then bake as directed.
Freezing Easy Low Carb Pizza Casserole – Cheesy & Family-Approved
Freeze individual portions for up to 3 months. Thaw overnight in the fridge before reheating.
How to Reheat Without Drying It Out
Oven: Reheat in the oven at 350°F (175°C) for 15-20 minutes. Microwave: Reheat in the microwave for 1-2 minutes, then crisp under the broiler for 2-3 minutes.
Recipe Notes
- Chef tip: For a gluten-free option, use a gluten-free pizza sauce and ensure your cheese is gluten-free.
- Best substitution: Substitute the ground beef with ground turkey or Italian sausage for a different flavor profile.
- Make-ahead: Assemble the casserole up to 24 hours ahead. Store in the fridge, then bake as directed.
- Scaling: This recipe can be easily doubled to serve a larger crowd.
- Troubleshooting: If the cheese is browning too quickly, cover the casserole loosely with aluminum foil.
Want to level up this recipe?
Pizza cutter — Makes slicing and serving this casserole a breeze. → Check price on Amazon
Easy Low Carb Pizza Casserole – Cheesy & Family-Approved

Ingredients
Main Ingredients
- 1 lb ground beef
- 1 cup shredded mozzarella cheese
- 1 cup shredded cheddar cheese
- 1 cup pizza sauce
- 1 cup shredded pepperoni
Seasonings
- 1 tsp Italian seasoning
- 1 tsp garlic powder
- 1 tsp onion powder
- Salt and pepper to taste
Optional Toppings
- Sliced bell peppers
- Sliced onions
- Mushrooms
- Olives
- Artichoke hearts
Instructions
- Step 1: Preheat your oven to 375°F (190°C). In a large non-stick skillet, cook the ground beef over medium heat until browned. Drain excess fat.
- Step 2: Stir in the Italian seasoning, garlic powder, onion powder, salt, and pepper. Cook for an additional 2 minutes.
- Step 3: Spread the cooked meat evenly in the bottom of a greased 9×13-inch casserole dish.
- Step 4: Spread the pizza sauce over the meat, then sprinkle with half of the mozzarella and cheddar cheeses.
- Step 5: Add your desired toppings, then sprinkle with the remaining cheese.
- Step 6: Bake for 20-25 minutes, or until the cheese is bubbly and golden. Let it rest for 5 minutes before serving.
Notes
- Chef tip: For a gluten-free option, use a gluten-free pizza sauce and ensure your cheese is gluten-free.
- Best substitution: Substitute the ground beef with ground turkey or Italian sausage for a different flavor profile.
- Make-ahead: Assemble the casserole up to 24 hours ahead. Store in the fridge, then bake as directed.
- Scaling: This recipe can be easily doubled to serve a larger crowd.
- Troubleshooting: If the cheese is browning too quickly, cover the casserole loosely with aluminum foil.
Storage
- Fridge: Store leftovers in an airtight container in the fridge for up to 4 days.
- Freezer: Freeze individual portions for up to 3 months. Thaw overnight in the fridge before reheating.
- Oven reheat: Reheat in the oven at 350°F (175°C) for 15-20 minutes.
- Microwave reheat: Reheat in the microwave for 1-2 minutes, then crisp under the broiler for 2-3 minutes.
- Make ahead: You can assemble this casserole up to 24 hours ahead. Store in the fridge, then bake as directed.
Nutrition Per Serving
- Calories: 380
- Protein: 26g
- Fat: 28g
- Carbs: 8g
- Fiber: 1g
- Sugar: 3g
- Sodium: 900mg
- Cholesterol: 110mg
- Sat. Fat: 15g
Nutritional values are estimates only. Actual values may vary by brand and portion size.
Easy Low Carb Pizza Casserole – Cheesy & Family-Approved FAQs
Yes, you can assemble it up to 24 hours ahead. Store in the fridge, then bake as directed.
Overcooking can cause the casserole to dry out. Keep an eye on it to prevent this.
Yes, freeze individual portions for up to 3 months. Thaw overnight in the fridge before reheating.
While you can't cook the entire casserole in the air fryer, you can air fry the meat and toppings separately, then assemble and bake in the oven.
You can use marinara sauce or even salsa as a substitute for pizza sauce.
A Warm Final Note
I can’t wait for you to try Easy Low Carb Pizza Casserole – Cheesy & Family-Approved and see how effortlessly it comes together. When you make it, pop back here and leave a rating or share how it turned out — I love hearing from you!






